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Also known as thioctic acid, this unique water and fat‐soluble nutrient has been shown to support insulin sensitivity as well as promote a healthy nervous system. This is critical, especially in the maintenance of long‐term nerve health. Of the two enantiomers of alpha lipoic acid, the “R”, or natural form, is better absorbed by the intestinal tract.
The fruit of the Phyllanthus emblica tree, also known as Indian gooseberry, has been used for centuries for its flavoring properties. Recently, researchers discovered that certain polyphenols found in amla can help support healthy blood sugar levels in addition to promoting a healthy nervous system.
Bilberries, known for their bittersweet taste, have long been used in a variety of medicinal capacities. In addition to supporting ocular health, certain anthocyanosides found in these berries have the capability to support healthy insulin sensitivity. This is thought to be done by drastically reducing the amount of inflammatory cytokines in circulation, supporting insulin’s ability to bind to its receptors.
Another member of the B vitamin family is biotin, otherwise known as vitamin B7 or vitamin H. Biotin is directly involved in various metabolic pathways in humans and animals, and when taken in certain amounts in supplemental form it has been shown to effectively reduce the amount of glycogen and gluconeogenesis (synthesis of glucose from other substrates).
Momordica charantia is a vine fruit well‐reputed for its beneficial properties associated with blood sugar metabolism. In many cases, Type 1 diabetics benefit from support with particular protein kinases that are directly involved in glucose metabolism mechanisms, particularly in the liver. Researchers have found that certain triterpenoids in bitter melon have the ability to promote activation of these enzymes, helping support healthy blood glucose levels.
Chromium in its trivalent state helps support healthy insulin function. When complexed to picolinic and/or nicotinic acids, chromium has a way of helping support sensitivity of the insulin receptor, maintaining healthy movement of glucose from the bloodstream into the target cell.
The bark of Cinnamomum cassia and zeylanicum have been used across the world for medicinal purposes. Although the mechanism is not yet fully understood, cinnamaldehyde and eugenol, two key components of cinnamon, have been demonstrated in research studies to help support healthy blood glucose levels.
The Lagerstroemia speciose plant (or banaba) contains in its leaves corosolic acid, which has been shown to enhance cellular uptake of glucose, impair the hydrolysis of sucrose and starches within the gut, and decrease gluconeogenesis.
This ingredient is part of a group of isomers known as inositol, which are involved in the second messenger cascade of the insulin response. This means that when insulin “rings” the insulin receptor on a given cell, inositol is involved in the pathway in which glucose is transported inside the cell. Due to its ability to help facilitate this critical function, D‑chiro‑Inositol is a key ingredient in Roya.
The Trigonella foenum‑graecum plant has been used for thousands of years to maintain healthy blood glucose. Certain alkaloids found in fenugreek have been shown to help support healthy blood glucose levels, while certain amino acids found in the plant’s seeds and leaves can stimulate insulin secretion at all levels of cellular organization. This combination of properties makes fenugreek an especially powerful ingredient.
This mineral has the unique ability, when in its proper oxidation state, to help maintain healthy blood glucose levels by allowing the appropriate amounts of glucose uptake from the bloodstream to the inside of involved tissues. Vanadium is in one of its most biologically active forms, as it is chelated to certain amino acids.
Retinyl palmitate is one of many forms of vitamin A and is typically used to support healthy eyes and skin while providing immune system support. Type 1 diabetics typically have trouble obtaining adequate amounts of vitamin A from their diets, especially when beta carotene is the source.
Type 1 diabetics tend to be deficient in vitamin B1 — along with the other members of the vitamin B family, vitamin B1 mainly acts as a cofactor to many different enzymes in our bodies that perform multiple functions. Thiamine is a water‐soluble vitamin and has a higher rate of tissue and bloodstream clearance than fat‐soluble nutrients.
Pyridoxal‑5‑phosphate (the biologically active form of vitamin B6) is another member of the B vitamin family that has a higher rate of clearance from bodily tissues than fat‐soluble vitamins, especially in those with Type 1 diabetes. Vitamin B6 is mainly involved in acting as the “activator” of several enzymes that synthesize neurotransmitters and hormones, among other necessary bodily chemicals.
Cholecalciferol is the biologically active form of vitamin D. Similar to vitamins A and E, this fat‐soluble vitamin has been known to be found in lower quantities in those with Type 1 diabetes. In addition to filling a typical deficiency, vitamin D3 has been demonstrated to support healthy blood glucose levels and insulin sensitivity, making it a critical component of Roya.
Also known as tocopherol or tocotrienol, vitamin E and its congeners help protect virtually every cell in our bodies from oxidation. Like vitamin A, many of those who suffer from Type 1 diabetes have trouble obtaining and managing normal amounts of vitamin E within their bodies. Thus, supplementation is greatly advised.
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